Secondary Syphilis Presenting As Palmoplantar Psoriasis

A case of secondary syphilis mimicking palmoplantar psoriasis in HIV infected patient*

Due to diverse clinical and histopathological presentations, diagnosis of secondary syphilis can occasionally prove challenging. Variable clinical presentations of secondary syphilis in HIV disease may result in an incorrect diagnosis and an inappropriate treatment regimen. Similarly, the histology of secondary syphilitic lesions may show considerable variation, depending on the clinical morpho...

A secondary syphilis rash with scaly target lesions

A 40-year-old man reported a 5-day history of fever and malaise, followed by a pruritic generalized rash. He had well-demarcated erythematous papules and plaques with scaling. The patient was diagnosed with secondary syphilis. The skin biopsy showed a psoriasiform lichenoid dermatitis with plasma cells. The anti-T. pallidum antibody confirmed the presence of spirochetes. He was also found to be...

Pustulocrustaceous secondary syphilis.

Sir, A generalized pustular eruption in an adult may be the presenting feature of viral infections, drug eruptions, psoriasis, subcorneal pustular dermatosis or impetigo herpetiformis. Rarely, generalized pustulation is a manifestation of secondary syphilis. We present here a case of secondary syphilis with a dramatic generalized eruption of pustules followed by impetiginous lesions. The classi...

A case of palmoplantar lichen planus mimicking secondary syphilis.

Lichen planus is a chronic inflammatory disease that affects skin, mucous membranes, hairs, and nails. According to the site of involvement, lichen planus can be subdivided into palmoplantar, mucosal, nail, or scalp types. Palmoplantar lichen planus is a rare subtype of lichen planus which may create difficulty in diagnosis, as the lesion is limited to the palms and soles. We report a case of a...

Early congenital syphilis presenting with vesicobullous eruptions beyond palmoplantar regions.